Moiramide B

CAS No. 155233-31-1

Moiramide B( —— )

Catalog No. M36494 CAS No. 155233-31-1

Moiramide B is a potent acetyl coenzyme A carboxylase (ACC) inhibitor (IC50:6 nM) with antimicrobial activity, strongly inhibiting Gram-positive bacteria but weakly inhibiting Gram-negative bacteria.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 1137 Get Quote
5MG 1492 Get Quote
25MG 2364 Get Quote
50MG 2926 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Moiramide B
  • Note
    Research use only, not for human use.
  • Brief Description
    Moiramide B is a potent acetyl coenzyme A carboxylase (ACC) inhibitor (IC50:6 nM) with antimicrobial activity, strongly inhibiting Gram-positive bacteria but weakly inhibiting Gram-negative bacteria.
  • Description
    Moiramide B is a potent acetyl-CoA carboxylase (ACC) inhibitor with an IC50 value of 6 nM. Moiramide B has antibacterial activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Acetyl-CoA Carboxylase | Antibiotic
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    155233-31-1
  • Formula Weight
    453.53
  • Molecular Formula
    C25H31N3O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C([C@@H](NC(C[C@H](NC(/C=C/C=C/C)=O)C1=CC=CC=C1)=O)[C@@H](C)C)(=O)[C@H]2[C@H](C)C(=O)NC2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Cifone MT, et, al. Heterobivalent Inhibitors of Acetyl-CoA Carboxylase: Drug Target Residence Time and Time-Dependent Antibacterial Activity. J Med Chem. 2022 Dec 22;65(24):16510-16525.??
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